Differential inhibition of postnatal brain,spinal cord and body growth by a growth hormone antagonist

Background  

Growth hormone (GH) plays an incompletely understood role in the development of the central nervous system (CNS). In this study, we use transgenic mice expressing a growth hormone antagonist (GHA) to explore the role of GH in regulating postnatal brain, spinal cord and body growth into adulthood. The GHA transgene encodes a protein that inhibits the binding of GH to its receptor, specifically antagonizing the trophic effects of endogenous GH.     

Effect of three-body forces on the lattice dynamics of noble metals

A simple method to generate an effective electron-ion interaction pseudopotential from the energy wave number characteristic obtained by first principles calculations has been suggested. This effective potential has been used, in third order perturbation, to study the effect of three-body forces on the lattice dynamics of noble metals. It is found that three-body forces, in these metals, do play an important role. The inclusion of such three-body forces appreciably improves the agreement between the experimental and theoretical phonon dispersion curves.     

Degenerate elliptic boundary value problems

In this paper we find conditions that guarantee that regular boundary value problems for elliptic differential-operator equations of the second order in an interval are coercive and Fredholm, and we prove the compactness of a resolvent. We apply this result to find some algebraic conditions that guarantee that regular boundary value problems for degenerate elliptic differential equations of the second order in cylindrical domains have the same properties. Note that considered boundary value conditions are nonlocal and are differential only in their principal part, and a domain is nonsmooth.